Cleveland Diagnostics is developing technology to detect cancer early, when it can be treated and cured

 
 

 

Early Detection Works

Generally, if cancer is found early, 90 percent survive. If cancer is found late, 10 percent survive. Earlier detection leads to earlier, more precise treatment that may treat and cure cancer.

However, there are few effective early detection methods for cancer.

We're here to change that. 

 

Survival (%) Correlated with Stage of Diagnosis*

 

How We're Different

We've taken an "out-of-the-box" approach to detecting cancer. Today, most laboratories rely on the overall expression of biomarkers. These biomarkers, often proteins, are typically overexpressed in the context of cancer. However, it has become clear that a number of non-cancerous conditions can also cause an overexpression of these biomarkers. Therefore, false positives are very common. For example, PSA, which is the biomarker used for prostate cancer, can also be overexpressed due to inflammation, benign prostatic hyperplasia, urinary tract infection, and even something as common as riding a bike.

Our approach to detecting cancer at the earliest stage is to determine not just the overall expression of these biomarkers, but rather their origin. We have developed proprietary technology that separates protein isoforms, allowing us to investigate proteins based on structure, not concentration.

 

 

*Surveillance, Epidemiology and End Results (SEER) Program, 1973-2006; Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD, 2006.